A Survey of Intron Research in Genetics
نویسندگان
چکیده
A brief survey of biological research on non-coding DNA is presented here. There has been growing interest in the eeects of non-coding segments in evolutionary algorithms (EAs). To better understand and conduct research on non-coding segments and EAs, it is important to understand the biological background of such work. This paper begins with a review of basic genetics and terminology, describes the diierent types of non-coding DNA, and then surveys recent intron research.
منابع مشابه
P-122: The Effect of Beta Globin Intron on Human LH Hormone Expression in CHO Cells
Background Luteinizing hormone (LH) is a heterodimeric glycoprotein composed of alpha and beta subunits.This hormone is secreted from the pituitary gland. LH, in women triggers Menstrual cycle and ovulation. In men, LH stimulates production of testosterone, which plays a specialized role in sperm production. Up to day, LH hormone have produced in different ways such as codon optimization and al...
متن کاملP-127: The Effect of Beta Globin Intron on Human FSH Hormone Expression in CHO Cells
Background Follicle stimulating hormone (FSH)- a hetrodimeric glycoprotein- is secreted by pituitary gland. This hormone stimulates growth and maturation of the follicles in females and sperms in male. Up to now, glycoprotein hormones such as FSH have produced in different cell lines. Among of the mammalian expression systems, the Chinese hamster ovary cells (CHO) have taken into consideration ...
متن کاملGenotyping of Intron 22 and Intron 1 Inversions of Factor VIII Gene Using an Inverse-Shifting PCR Method in an Iranian Family with Severe Haemophilia A
Abstract Background: Haemophilia A (HA) is an X-linked bleeding disorder caused by the absence or reduced activity of coagulation factor VIII (FVIII). Coagulation factors are a group of related proteins that are essential for the formation of blood clots. The aim of this study was to genotype the coagulation factor VIII gene mutations using Inverse Shifting PCR (IS-PCR) in an Iranian family ...
متن کاملAssociation between Thrombophilic Gene Polymor-phisms and Recurrent Pregnancy Loss in Iranian Women
Background: Recurrent pregnancy loss (RPL) is a common problem among couples, and acquired thrombophilia is the well-known etiology of RPL. The aim of this study was to establish the association between inherited thrombophilic gene polymorphisms and RPL. Methods: This case-control study was conducted on 50 women with unexplained RPL and 50 parous women with no history of miscarriage (age range...
متن کاملAssociation between bovine lactoferrin gene variant and somatic cell count in milk based on EcoRI restriction site
Mastitis is one of the most serious and costly diseases affecting dairy cattle production. In the present study, effects of a lactoferrin gene polymorphism (intron 6) on milk somatic cell count (SCC) and subclinical mastitis was investigated in 121 Holstein dairy cattle. Two alleles of A and B and two genotypes of AA and AB were found in an EcoRI recognized single nucleotide polymorphism in int...
متن کامل